5, 121126 2010. Liu, J. et al. Metallization of branched DNA origami for nanoelectronic circuit fabrication. ACS Nano 5, 22402247 2011. Pilo Pais, M. P, , India Has contributed: QSAR Guided Semi synthesis and In Vitro Validation of Anticancer Activity in Ursolic Acid DerivativesCancer is programming second most popular causes of death among non communicable sicknesses, and programming incidenceof cancer has been dramatically higher in programming past a number of many years which is principally attributed tolifestyle changes . Cancer can be cured by diverse strategies, and programming five year relative survivalrate of all cancers has greater considerably in recent times . However, programming complexity and refractorynature of programming disorder itself, along with programming drug resistance, side outcomes, and non true toxicityof chemotherapy agents, calling for perpetually innovate programming advancement of new cancer treatmentschemes and novel anticancer agents . Indazoles and indoles, bicyclic compounds with fused benzene and pyrazole/pyrrole nucleus, possessremarkable structural and mechanistic diversity and will exert programming anticancer exercise via inhibitingDNA topoisomerase, histone deacetylase, histone acetyltransferases, myeloid cell leukemia 1, proviralinsertion site in moloney murine leukemia virus, silent mating type guidance regulation 2 homolog and tubulin . Axitinib, lonidamine and pazopanib are indazole based anticancer agents, while vinblastine, vincristine, anlotinib andosimertinib contain indole moiety. Accordingly, indazoles and indoles occupy an important position in programming discovery of novelanticancer agents.